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Moreover, in the SNc pharmacological activation of dopamine receptor D3 with a selective agonist -7-hydroxy-N,N-di-n-propyl-2aminotetralin- induced cell proliferation and maturation towards dopaminergic phenotype (Van Kampen and Eckman, 2006), thus suggesting the possible occurrence of adult neurogenesis in this region under the pathological conditions in PD (Arias-Carrion et al., 2009)

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MTR (methionine synthase) and MTRR (methionine synthase reductase) code for two enzymes that work together in the methylation cycle